Ted Danson has had his share of leading ladies throughout his Hollywood career and says he is finally working with his dream girl on the upcoming season of HBO's Bored to Death - it's his wife, Mary Steenburgen! "She [plays] my vocal coach, and, basically, I think she never teaches me anything because we always end up falling into bed!" he jokes. "It's so cool."

Rachael asks Ted if he'll answer some audience questions and one viewer asks if he has advice for Charlie Sheen. "I almost can't go there," Ted says, "because my heart goes out to family, my heart goes out to him and I don't know that I could add anything worthwhile ... Maybe we should pull back."

Ted takes another audience question, and the fan wonders about the potential for a Cheers reunion show. He says it was discussed when his fellow "bar mate", Kelsey Grammer, was ending his run with the show's spinoff, Frasier. "We all thought, what a great idea to have Kelsey walk back into the bar in Boston with us all older!" But, he says the studio was not as enthusiastic. "They wisely said, 'No! Why mess with it?'"

When he's not on a movie or TV set, Ted is actively involved in the campaign to protect the oceans. He hopes his book, Oceana, will inspire everyone to get involved. It includes practical tips without being intimidating. "If you want to do something about it and you do it with a heavy heart and you're full of fear, you're not going to get anything done," he says. "You have to approach, especially the tough stuff, with a light heart, you know? So, go to the beach, go have a seafood dinner that you love, remember why you love the ocean - then tackle the work."

More with Ted: Head backstage and find out 3 things you don't know about him, including his idea for the perfect tattoo!